Which of the following brought increased public attention to the problems with the IRB system?
A. HHS Inspector General Report of 1998.
B. 1983 Presidential Commission Report.
C. “Shut Downs” by OHRP.
D. Death of Jesse Gelsinger.
The correct answer is option D.
The Death of Jesse Gelsinger brought increased public attention to the problems with the IRB system.
IRB is the Institutional Review Board which is responsible for the protection of rights of human subjects in a research study. The primary function of this organization is to protect and prevent the rights of human subjects in any research study.
Jesse Gelsinger was enrolled in a clinical trial at the University of Pennsylvania. He died out during the clinical trial, which brought the attention of the public.
At the University of Pennsylvania, researchers were developing a cure for severe diseases in infants. So they used Jesse Gelsinger as a human subject in a clinical trial. Adenoviral vector was injected to him. As a result of which he died out after hour days later of a gene trial.
So this case was brought to public attention which increased the problems with the IRB system.